Radiologist recommendations for chest CT have high clinical yield

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Findings show that radiologist RAIs after chest X-rays represent valuable contributions to patient care

A new study published online in the journal Radiology, reveals that considerable percentage of patients who are recommended by radiologists for chest computed tomography (CT) to evaluate abnormal findings on outpatient chest X-rays have clinically relevant findings, including cancer.

Researchers said the findings show that radiologist recommendations for additional imaging (RAIs) after chest X-rays represent valuable contributions to patient care.

RAIs, which have grown 200 per cent since 1995, have attracted scrutiny in recent years as healthcare moves from volume-driven to value-based payment models. The scrutiny makes it increasingly important for the radiology community to validate the clinical impact of its work, said study author, Dr Tarik K Alkasab, from Massachusetts General Hospital and Harvard Medical School in Boston.

“There has been a great deal of research on how radiologists recommend an imaging exam, but little on what comes out of the exams that they recommend. Prior studies were very broad, so in our study we tried to focus on a specific clinical scenario,” said Dr Alkasab.

Dr Alkasab and colleagues looked at chest X-rays, one of the most common outpatient diagnostic imaging studies performed in the US. As many as half of all RAIs arising from thoracic diagnostic exams are prompted by chest X-rays.

The researchers combed through more than 29,000 reports of outpatient chest X-rays performed at a large academic centre over one year to identify studies that included a recommendation for a chest CT. They found that radiologists interpreting outpatient chest X-rays made recommendations for CT in 4.5 per cent of cases—a result in line with existing research. Increasing patient age and positive smoking history were associated with an increased likelihood of a chest CT recommendation.

When the researchers looked at the chest CTs obtained within one year of the index chest X-ray, they found that 41.4 per cent detected a corresponding abnormality requiring treatment or further diagnostic workup. One in every 13 yielded a corresponding abnormality representing a newly-diagnosed, biopsy-proven malignancy.

“In this era of concern about radiation dose risk, these findings suggest that the extremely low predicted risk of radiation-induced cancer associated with a chest CT is orders of magnitude less than the potential clinical benefits,” said study co-author Dr H Benjamin Harvey, from Massachusetts General Hospital and Harvard Medical School.

“If ordering physicians see a recommendation for chest CT, they need to ensure that the patient gets the recommended imaging,” added Dr Harvey.

More than one-third of patients in the study group who were recommended for follow-up chest CT did not receive the exam within one year—an oversight that could result in missed or delayed diagnoses, the researchers said.

“More research is needed to understand the possible reasons for the less-than-optimal adherence to RAIs after chest X-ray. One thing we’re looking at is how the recommendation language affects recommendation adherence,” Dr Harvey said.

The researchers hope that their study helps improve awareness of the importance of follow-up CT.

“These results show that radiologists should be confident their recommendations are adding value and protecting patients,” said Dr Alkasab.